Gene
yrk
- ID
- ZDB-GENE-030131-9517
- Name
- Yes-related kinase
- Symbol
- yrk Nomenclature History
- Previous Names
-
- fj84d04
- wu:fj84d04 (1)
- zgc:92165
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in macrophage chemotaxis. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Is expressed in blood island; cardiovascular system; head; mesoderm; and post-vent region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159437 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Domain | IPR035693 | Tyrosine-protein kinase Fgr, SH2 domain |
| Family | IPR050198 | Non-receptor tyrosine kinases involved in cell signaling |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Non-receptor tyrosine kinases involved in cell signaling | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | SH2 domain | SH2 domain superfamily | SH3 domain | SH3-like domain superfamily | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase Fgr, SH2 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8AWF1
|
525 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
yrk-201
(1)
|
Ensembl | 3,705 nt | ||
| mRNA |
yrk-203
(1)
|
Ensembl | 406 nt | ||
| mRNA |
yrk-204
(1)
|
Ensembl | 3,768 nt | ||
| mRNA |
yrk-205
(1)
|
Ensembl | 567 nt | ||
| mRNA |
yrk-206
(1)
|
Ensembl | 717 nt | ||
| mRNA |
yrk-207
(1)
|
Ensembl | 3,028 nt | ||
| mRNA |
yrk-208
(1)
|
Ensembl | 3,524 nt | ||
| ncRNA |
yrk-004
(1)
|
Ensembl | 539 nt |
Interactions and Pathways
No data available
Plasmids