Gene

bcat1

ID

ZDB-GENE-030131-9358

Name

branched chain amino-acid transaminase 1, cytosolic

Symbol

bcat1 Nomenclature History

Previous Names

fj66g02
wu:fj66g02
zgc:73157

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to enable branched-chain-amino-acid transaminase activity. Predicted to be involved in leucine biosynthetic process and valine biosynthetic process. Predicted to act upstream of or within amino acid biosynthetic process and branched-chain amino acid biosynthetic process. Predicted to be active in mitochondrion. Is expressed in central nervous system; liver; muscle; and neural tube. Orthologous to human BCAT1 (branched chain amino acid transaminase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73157 (3 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bcat1 Human Ortholog

No data available

Associated With bcat1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018300	Aminotransferase, class IV, conserved site
Family	IPR001544	Aminotransferase class IV
Family	IPR005786	Branched-chain amino acid aminotransferase II
Family	IPR033939	Branched-chain aminotransferase
Homologous_superfamily	IPR036038	Aminotransferase-like, PLP-dependent enzymes
Homologous_superfamily	IPR043131	Branched-chain-amino-acid aminotransferase-like, N-terminal
Homologous_superfamily	IPR043132	Branched-chain-amino-acid aminotransferase-like, C-terminal

Domain Details Per Protein

Protein	Length	Aminotransferase class IV	Aminotransferase, class IV, conserved site	Aminotransferase-like, PLP-dependent enzymes	Branched-chain amino acid aminotransferase II	Branched-chain-amino-acid aminotransferase-like, C-terminal	Branched-chain-amino-acid aminotransferase-like, N-terminal	Branched-chain aminotransferase
UniProtKB:Q6PC10 InterPro	385
UniProtKB:A0A8M2BBX5 InterPro	373
UniProtKB:A0A8M3AYQ7 InterPro	375

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	bcat1-201 (1) Ensembl	Ensembl	2,001 nt	Select Tool ZFIN BLAST
mRNA	bcat1-202 (1) Ensembl	Ensembl	780 nt	Select Tool ZFIN BLAST
mRNA	bcat1-205 (1) Ensembl	Ensembl	785 nt	Select Tool ZFIN BLAST
ncRNA	bcat1-004 (1) Ensembl	Ensembl	501 nt	Select Tool ZFIN BLAST
ncRNA	bcat1-005 (1) Ensembl	Ensembl	832 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations