Gene
moxd1
- ID
- ZDB-GENE-030131-9320
- Name
- monooxygenase, DBH-like 1
- Symbol
- moxd1 Nomenclature History
- Previous Names
-
- fj65c11
- si:dkeyp-119b4.5
- wu:fj65c11
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable copper ion binding activity and dopamine beta-monooxygenase activity. Predicted to be involved in dopamine catabolic process; norepinephrine biosynthetic process; and octopamine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in extracellular space and secretory granule membrane. Orthologous to human MOXD1 (monooxygenase DBH like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000323 | Copper type II, ascorbate-dependent monooxygenase, N-terminal |
| Domain | IPR005018 | DOMON domain |
| Domain | IPR024548 | Copper type II ascorbate-dependent monooxygenase, C-terminal |
| Domain | IPR045266 | Copper-dependent monooxygenases, DOMON domain |
| Family | IPR000945 | Dopamine beta-hydroxylase-like |
| Family | IPR028460 | Tyramine beta-hydroxylase/Dopamine beta-hydroxylase |
| Homologous_superfamily | IPR008977 | PHM/PNGase F domain superfamily |
| Homologous_superfamily | IPR014784 | Copper type II, ascorbate-dependent monooxygenase-like, C-terminal |
| Homologous_superfamily | IPR036939 | Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Copper-dependent monooxygenases, DOMON domain | Copper type II ascorbate-dependent monooxygenase, C-terminal | Copper type II, ascorbate-dependent monooxygenase-like, C-terminal | Copper type II, ascorbate-dependent monooxygenase, N-terminal | Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily | DOMON domain | Dopamine beta-hydroxylase-like | PHM/PNGase F domain superfamily | Tyramine beta-hydroxylase/Dopamine beta-hydroxylase |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5TZ24
|
614 |
Interactions and Pathways
No data available
Plasmids
No data available