Gene
snx3
- ID
- ZDB-GENE-030131-921
- Name
- sorting nexin 3
- Symbol
- snx3 Nomenclature History
- Previous Names
-
- wu:fb53a08
- zgc:123189
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have phosphatidylinositol-3-phosphate binding activity. Involved in erythrocyte differentiation; heme biosynthetic process; and hemoglobin biosynthetic process. Predicted to localize to early endosome membrane and retromer complex. Human ortholog(s) of this gene implicated in syndromic microphthalmia. Is expressed in digestive system; hematopoietic system; and vascular endothelium. Orthologous to human SNX3 (sorting nexin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Chen et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phox homology | PX domain superfamily | Sorting Nexin | Vertebrate SNX3, PX domain |
|---|---|---|---|---|---|
|
UniProtKB:Q3B7E7
|
162 |
Interactions and Pathways
No data available
Plasmids
No data available