Gene

tuba5

ID
ZDB-GENE-030131-9167
Name
tubulin alpha 5
Symbol
tuba5 Nomenclature History
Previous Names
  • tuba8l (1)
  • fb02d10
  • wu:fb02d10
  • zgc:85698 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to cytoplasm and microtubule. Is expressed in brain.
Genome Resources
Note
Analysis by Dave Webb suggests this gene is orthologous to the mammalian TUBA5 (a pseudogene in human). There is synteny at least as far back as Osteichtyhes as this gene invariably resides at CYB5R1>...ADIPOR1>...KHL12>...RABIF>...tuba*>...MGAT4E<...KDM5B>
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tuba5 Human Ortholog
No data available
Associated With tuba5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
Family IPR002452 Alpha tubulin
Homologous_superfamily IPR008280 Tubulin/FtsZ, C-terminal
Homologous_superfamily IPR023123 Tubulin, C-terminal
Homologous_superfamily IPR036525 Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily IPR037103 Tubulin/FtsZ-like, C-terminal domain
Domain Details Per Protein
Protein Length Alpha tubulin Tubulin Tubulin, conserved site Tubulin, C-terminal Tubulin/FtsZ, 2-layer sandwich domain Tubulin/FtsZ, C-terminal Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily Tubulin/FtsZ-like, C-terminal domain
UniProtKB:Q6NWI0 449
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations