Gene

tuba5

ID

ZDB-GENE-030131-9167

Name

tubulin alpha 5

Symbol

tuba5 Nomenclature History

Previous Names

tuba8l (1)
fb02d10
wu:fb02d10
zgc:85698 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have GTP binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to cytoplasm and microtubule. Is expressed in brain.

Genome Resources

Note

Analysis by Dave Webb suggests this gene is orthologous to the mammalian TUBA5 (a pseudogene in human). There is synteny at least as far back as Osteichtyhes as this gene invariably resides at CYB5R1>...ADIPOR1>...KHL12>...RABIF>...tuba*>...MGAT4E<...KDM5B>

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:85698 (1 image)
IMAGE:6892915 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tuba5 Human Ortholog

No data available

Associated With tuba5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017975	Tubulin, conserved site
Domain	IPR003008	Tubulin/FtsZ, GTPase domain
Domain	IPR018316	Tubulin/FtsZ, 2-layer sandwich domain
Family	IPR000217	Tubulin
Family	IPR002452	Alpha tubulin
Homologous_superfamily	IPR008280	Tubulin/FtsZ, C-terminal
Homologous_superfamily	IPR023123	Tubulin, C-terminal
Homologous_superfamily	IPR036525	Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily	IPR037103	Tubulin/FtsZ-like, C-terminal domain

Domain Details Per Protein

Protein	Length	Alpha tubulin	Tubulin	Tubulin, conserved site	Tubulin, C-terminal	Tubulin/FtsZ, 2-layer sandwich domain	Tubulin/FtsZ, C-terminal	Tubulin/FtsZ, GTPase domain	Tubulin/FtsZ, GTPase domain superfamily	Tubulin/FtsZ-like, C-terminal domain
UniProtKB:Q6NWI0 InterPro	449

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tuba5-201 (1) Ensembl	Ensembl		1,803 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations