Gene
setd3
- ID
- ZDB-GENE-030131-9137
- Name
- SET domain containing 3, actin histidine methyltransferase
- Symbol
- setd3 Nomenclature History
- Previous Names
-
- fb01d12
- wu:fb01d12
- zgc:63842
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits histone methyltransferase activity (H3-K36 specific) and transcription coactivator activity. Involved in peptidyl-lysine methylation and positive regulation of transcription, DNA-templated. Predicted to localize to cytoplasm and nuclear chromatin. Orthologous to human SETD3 (SET domain containing 3, actin histidine methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR015353 | Rubisco LSMT, substrate-binding domain |
| Domain | IPR044428 | SETD3, SET domain |
| Family | IPR025785 | Actin-histidine N-methyltransferase SETD3 |
| Family | IPR050600 | SETD3/SETD6 methyltransferase |
| Homologous_superfamily | IPR036464 | Rubisco LSMT, substrate-binding domain superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | Actin-histidine N-methyltransferase SETD3 | Rubisco LSMT, substrate-binding domain | Rubisco LSMT, substrate-binding domain superfamily | SETD3/SETD6 methyltransferase | SETD3, SET domain | SET domain | SET domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SXS7
|
596 |
Interactions and Pathways
No data available
Plasmids
No data available