Gene

setd3

ID
ZDB-GENE-030131-9137
Name
SET domain containing 3, actin histidine methyltransferase
Symbol
setd3 Nomenclature History
Previous Names
  • fb01d12
  • wu:fb01d12
  • zgc:63842
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits histone methyltransferase activity (H3-K36 specific) and transcription coactivator activity. Involved in peptidyl-lysine methylation and positive regulation of transcription, DNA-templated. Predicted to localize to cytoplasm and nuclear chromatin. Orthologous to human SETD3 (SET domain containing 3, actin histidine methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Diotel et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With setd3 Human Ortholog
No data available
Associated With setd3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001214 SET domain
Domain IPR015353 Rubisco LSMT, substrate-binding domain
Domain IPR044428 SETD3, SET domain
Family IPR025785 Actin-histidine N-methyltransferase SETD3
Family IPR050600 SETD3/SETD6 methyltransferase
Homologous_superfamily IPR036464 Rubisco LSMT, substrate-binding domain superfamily
Homologous_superfamily IPR046341 SET domain superfamily
Domain Details Per Protein
Protein Length Actin-histidine N-methyltransferase SETD3 Rubisco LSMT, substrate-binding domain Rubisco LSMT, substrate-binding domain superfamily SETD3/SETD6 methyltransferase SETD3, SET domain SET domain SET domain superfamily
UniProtKB:Q7SXS7 596
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA setd3-201 (1) Ensembl 3,816 nt
mRNA setd3-202 (1) Ensembl 2,494 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations