Gene

sema5a

ID

ZDB-GENE-030131-8969

Name

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Symbol

sema5a Nomenclature History

Previous Names

wu:fa95e03
wu:fi41a04 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have semaphorin receptor binding activity. Involved in axon extension. Predicted to localize to integral component of membrane. Is expressed in CaP motoneuron and myotome. Orthologous to human SEMA5A (semaphorin 5A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Hilario et al., 2009

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Hilario et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sema5a Human Ortholog

No data available

Associated With sema5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR016201	PSI domain
Family	IPR027231	Semaphorin
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat
Repeat	IPR002165	Plexin repeat

Domain Details Per Protein

Protein	Length	Plexin repeat	PSI domain	Sema domain	Sema domain superfamily	Semaphorin	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:F1R9L1 InterPro	1078
UniProtKB:A0A0R4IMM9 InterPro	1048
UniProtKB:A0A8M9PLV2 InterPro	1071

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sema5a-201 (1) Ensembl	Ensembl	5,242 nt	Select Tool ZFIN BLAST
mRNA	sema5a-202 (1) Ensembl	Ensembl	4,513 nt	Select Tool
mRNA	sema5a-204 (1) Ensembl	Ensembl	5,084 nt	Select Tool ZFIN BLAST
mRNA	sema5a-205 (1) Ensembl	Ensembl	3,890 nt	Select Tool ZFIN BLAST
ncRNA	sema5a-002 (1) Ensembl	Ensembl	806 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations