Gene
tollip
- ID
- ZDB-GENE-030131-8820
- Name
- toll interacting protein
- Symbol
- tollip Nomenclature History
- Previous Names
-
- fk22a02
- im:7145391
- wu:fk22a02
- zgc:76985
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin binding activity and ubiquitin conjugating enzyme binding activity. Involved in negative regulation of Wnt signaling pathway. Predicted to localize to cytoplasm. Orthologous to human TOLLIP (toll interacting protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145391 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR003892 | Ubiquitin system component CUE |
| Domain | IPR037301 | Toll-interacting protein, C2 domain |
| Domain | IPR041799 | Toll-interacting protein, CUE domain |
| Homologous_superfamily | IPR009060 | UBA-like superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | Toll-interacting protein, C2 domain | Toll-interacting protein, CUE domain | UBA-like superfamily | Ubiquitin system component CUE |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV43
|
276 | ||||||
|
UniProtKB:A0A0R4IVK4
|
252 | ||||||
|
UniProtKB:A0A0R4IZ33
|
276 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tollip-201
(1)
|
Ensembl | 918 nt | ||
| mRNA |
tollip-202
(1)
|
Ensembl | 1,305 nt |
Interactions and Pathways
No data available
Plasmids
No data available