Gene
tbxas1
- ID
- ZDB-GENE-030131-8805
- Name
- thromboxane A synthase 1 (platelet)
- Symbol
- tbxas1 Nomenclature History
- Previous Names
-
- wu:fk19d08
- zgc:136708
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have thromboxane-A synthase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in cerebral infarction and platelet-type bleeding disorder 14. Is expressed in heart. Orthologous to human TBXAS1 (thromboxane A synthase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Scherz et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ghosal hematodiaphyseal syndrome | Alliance | Ghosal hematodiaphyseal syndrome | 231095 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6TGT4
|
546 | |||||
|
UniProtKB:Q1LUX9
|
546 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tbxas1-201
(1)
|
Ensembl | 2,272 nt |
Interactions and Pathways
No data available
Plasmids
No data available