Gene

ncln

ID

ZDB-GENE-030131-8788

Name

nicalin

Symbol

ncln Nomenclature History

Previous Names

ncl1 (1)
LOC56926
nicalin
wu:fb07e09
wu:fk52a06
zgc:77236 (1)

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Involved in enteric nervous system development and negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry. Localizes to endoplasmic reticulum membrane. Is expressed in central nervous system and intestine. Orthologous to human NCLN (nicalin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:65783 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Gui et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ncln Human Ortholog

No data available

Associated With ncln Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007484	Peptidase M28
Family	IPR016574	Nicalin

Domain Details Per Protein

Protein	Length	Nicalin	Peptidase M28
UniProtKB:Q6NZ07 InterPro	572
UniProtKB:A0A8M2B8R6 InterPro	556
UniProtKB:A0A8M2B8L1 InterPro	557

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ncln-201 (1) Ensembl	Ensembl		2,560 nt	Select Tool ZFIN BLAST
mRNA	ncln-202 (1) Ensembl	Ensembl		2,554 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations