Gene

mpzl2b

ID
ZDB-GENE-030131-8774
Name
myelin protein zero-like 2b
Symbol
mpzl2b Nomenclature History
Previous Names
  • mpzl2
  • cb837 (1)
  • eva1
  • wu:fb07b02 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits identical protein binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 111. Is expressed in several structures, including digestive system; epidermis; periderm; pronephric duct; and sensory system. Orthologous to human MPZL2 (myelin protein zero like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Jayadev et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mpzl2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 111 Alliance Deafness, autosomal recessive 111 618145
Associated With mpzl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Family IPR000920 Myelin P0 protein-related
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin domain subtype Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin V-set domain Myelin P0 protein-related
UniProtKB:Q8JG36 199
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mpzl2b-201 (1) Ensembl 1,608 nt
ncRNA mpzl2b-002 (1) Ensembl 528 nt
ncRNA mpzl2b-003 (1) Ensembl 1,344 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations