Gene
mpzl2b
- ID
- ZDB-GENE-030131-8774
- Name
- myelin protein zero-like 2b
- Symbol
- mpzl2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits identical protein binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 111. Is expressed in several structures, including digestive system; epidermis; periderm; pronephric duct; and sensory system. Orthologous to human MPZL2 (myelin protein zero like 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb837 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Jayadev et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive nonsyndromic deafness 111 | Alliance | Deafness, autosomal recessive 111 | 618145 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003599 | Immunoglobulin domain subtype |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR013106 | Immunoglobulin V-set domain |
Family | IPR000920 | Myelin P0 protein-related |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Myelin P0 protein-related |
---|---|---|---|---|---|---|---|
UniProtKB:Q8JG36
|
199 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
mpzl2b-201
(1)
|
Ensembl | 1,608 nt | ||
ncRNA |
mpzl2b-002
(1)
|
Ensembl | 528 nt | ||
ncRNA |
mpzl2b-003
(1)
|
Ensembl | 1,344 nt |
Interactions and Pathways
No data available
Plasmids
No data available