Gene
tfg
- ID
- ZDB-GENE-030131-8410
- Name
- trafficking from ER to golgi regulator
- Symbol
- tfg Nomenclature History
- Previous Names
-
- wu:fb11c10
- zgc:55342
- zgc:77230
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable identical protein binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within COPII vesicle coating. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Orthologous to human TFG (trafficking from ER to golgi regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55342 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 2 | Alliance | Hereditary motor and sensory neuropathy, Okinawa type | 604484 |
| hereditary spastic paraplegia 57 | Alliance | ?Spastic paraplegia 57, autosomal recessive | 615658 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PB1 domain | PB1-like domain | Protein TFG | TFG, PB1 domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6P0G5
|
396 |
Interactions and Pathways
No data available
Plasmids
No data available