Gene
prg4a
- ID
- ZDB-GENE-030131-8295
- Name
- proteoglycan 4a
- Symbol
- prg4a Nomenclature History
- Previous Names
-
- fb08a02
- wu:fb08a02
- wu:fk21a06
- zgc:56698
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in immune response. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Is expressed in caudal fin. Orthologous to human PRG4 (proteoglycan 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nolte et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| camptodactyly-arthropathy-coxa vara-pericarditis syndrome | Alliance | Camptodactyly-arthropathy-coxa vara-pericarditis syndrome | 208250 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001212 | Somatomedin B domain |
| Domain | IPR020436 | Somatomedin B domain, chordata |
| Family | IPR051298 | Heme transport and cell adhesion protein |
| Homologous_superfamily | IPR036024 | Somatomedin B-like domain superfamily |
| Homologous_superfamily | IPR036375 | Hemopexin-like domain superfamily |
| Repeat | IPR018487 | Hemopexin-like repeats |
Domain Details Per Protein
| Protein | Length | Heme transport and cell adhesion protein | Hemopexin-like domain superfamily | Hemopexin-like repeats | Somatomedin B domain | Somatomedin B domain, chordata | Somatomedin B-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1PHS8
|
486 |
Interactions and Pathways
No data available
Plasmids
No data available