Gene

cart1

ID

ZDB-GENE-030131-8025

Name

cocaine- and amphetamine-regulated transcript 1

Symbol

cart1 Nomenclature History

Previous Names

fj47d09
si:dkey-37m8.9 (1)
wu:fj47d09

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have neuropeptide hormone activity. Predicted to be involved in several processes, including activation of MAPKK activity; adult feeding behavior; and negative regulation of appetite. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity. Is expressed in brain; diencephalon; and hypothalamus. Orthologous to human CARTPT (CART prepropeptide).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cart1 Human Ortholog

No data available

Associated With cart1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR009106	CART satiety factor
Homologous_superfamily	IPR036722	CART, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	CART, C-terminal domain superfamily	CART satiety factor
UniProtKB:A0A8N7T617 InterPro	175

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	cart1-201 (1) Ensembl	Ensembl		472 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations