Gene
osgep
- ID
- ZDB-GENE-030131-7880
- Name
- O-sialoglycoprotein endopeptidase
- Symbol
- osgep Nomenclature History
- Previous Names
-
- fj38e02
- si:ch211-214j24.11 (1)
- wu:fj38e02
- zgc:112527
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to localize to EKC/KEOPS complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Orthologous to human OSGEP (O-sialoglycoprotein endopeptidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112527 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Galloway-Mowat syndrome 3 | Alliance | Galloway-Mowat syndrome 3 | 617729 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017860 | Peptidase M22, conserved site |
| Domain | IPR000905 | Gcp-like domain |
| Family | IPR017861 | Kae1/TsaD family |
| Family | IPR034680 | tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaeal/eukaryotic |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
| Protein | Length | ATPase, nucleotide binding domain | Gcp-like domain | Kae1/TsaD family | Peptidase M22, conserved site | tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaeal/eukaryotic |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUE5
|
335 | |||||
|
UniProtKB:Q5RHZ6
|
335 |
Interactions and Pathways
No data available
Plasmids
No data available