Gene
clpp
- ID
- ZDB-GENE-030131-7860
- Name
- caseinolytic mitochondrial matrix peptidase proteolytic subunit
- Symbol
- clpp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATP-dependent peptidase activity; ATPase binding activity; and serine-type endopeptidase activity. Predicted to be involved in protein quality control for misfolded or incompletely synthesized proteins. Predicted to localize to endopeptidase Clp complex. Human ortholog(s) of this gene implicated in Perrault syndrome. Orthologous to human CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112333 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Perrault syndrome | Alliance | Perrault syndrome 3 | 614129 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018215 | ClpP, Ser active site |
| Active_site | IPR033135 | ClpP, histidine active site |
| Family | IPR001907 | ATP-dependent Clp protease proteolytic subunit |
| Family | IPR023562 | Clp protease proteolytic subunit /Translocation-enhancing protein TepA |
| Homologous_superfamily | IPR029045 | ClpP/crotonase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | ATP-dependent Clp protease proteolytic subunit | ClpP/crotonase-like domain superfamily | ClpP, histidine active site | Clp protease proteolytic subunit /Translocation-enhancing protein TepA | ClpP, Ser active site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q502B9
|
266 |
Interactions and Pathways
No data available
Plasmids
No data available