Gene

nme2a

ID
ZDB-GENE-030131-7656
Name
NME/NM23 nucleoside diphosphate kinase 2a
Symbol
nme2a Nomenclature History
Previous Names
  • nme2l
  • si:ch211-119c20.1
  • wu:fk59e05
  • zgc:73122
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have nucleoside diphosphate kinase activity. Predicted to be involved in purine nucleotide metabolic process; pyrimidine nucleotide metabolic process; and regulation of apoptotic process. Human ortholog(s) of this gene implicated in neuroblastoma; ovary epithelial cancer; and teratoma. Is expressed in several structures, including digestive system; female organism; gonad; male organism; and visual system. Orthologous to human NME1 (NME/NM23 nucleoside diphosphate kinase 1) and NME2 (NME/NM23 nucleoside diphosphate kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nme2a Human Ortholog
No data available
Associated With nme2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023005 Nucleoside diphosphate kinase, active site
Domain IPR034907 Nucleoside diphosphate kinase-like domain
Family IPR001564 Nucleoside diphosphate kinase
Homologous_superfamily IPR036850 Nucleoside diphosphate kinase-like domain superfamily
Domain Details Per Protein
Protein Length Nucleoside diphosphate kinase Nucleoside diphosphate kinase, active site Nucleoside diphosphate kinase-like domain Nucleoside diphosphate kinase-like domain superfamily
UniProtKB:A0A8M9PP44 178
UniProtKB:Q6PC37 153
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nme2a-201 (1) Ensembl 653 nt
mRNA nme2a-202 (1) Ensembl 560 nt
mRNA nme2a-203 (1) Ensembl 745 nt
mRNA nme2a-204 (1) Ensembl 1,509 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations