Gene
tctn2
- ID
- ZDB-GENE-030131-751
- Name
- tectonic family member 2
- Symbol
- tctn2 Nomenclature History
- Previous Names
-
- fb44f11
- si:ch211-89f7.3
- wu:fb44f11
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in cilium assembly; protein localization to ciliary transition zone; and smoothened signaling pathway. Predicted to localize to MKS complex. Human ortholog(s) of this gene implicated in Joubert syndrome 24 and Meckel syndrome 8. Orthologous to human TCTN2 (tectonic family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Liu et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Joubert syndrome 24 | Alliance | Joubert syndrome 24 | 616654 |
| Meckel syndrome 8 | Alliance | ?Meckel syndrome 8 | 613885 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tectonic | Tectonic domain |
|---|---|---|---|
|
UniProtKB:F1R5E2
|
702 |
Interactions and Pathways
No data available
Plasmids
No data available