Gene

amot

ID

ZDB-GENE-030131-7487

Name

angiomotin

Symbol

amot Nomenclature History

Previous Names

si:dkey-13f9.6 (1)
wu:fj21a07

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Involved in angiogenesis; blood vessel endothelial cell migration; and establishment or maintenance of cell polarity. Predicted to localize to bicellular tight junction; cytoplasmic vesicle; and plasma membrane. Orthologous to human AMOT (angiomotin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zheng et al., 2009

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With amot Human Ortholog

No data available

Associated With amot Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR024646	Angiomotin, C-terminal
Family	IPR009114	Angiomotin

Domain Details Per Protein

Protein	Length	Angiomotin	Angiomotin, C-terminal
UniProtKB:E7F8Q6 InterPro	968
UniProtKB:A0A8M2BL72 InterPro	1009

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	amot-201 (1) Ensembl	Ensembl	6,305 nt	Select Tool ZFIN BLAST
mRNA	amot-202 (1) Ensembl	Ensembl	6,065 nt	Select Tool
mRNA	amot-203 (1) Ensembl	Ensembl	6,459 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations