Gene
cimap1b
- ID
- ZDB-GENE-030131-7464
- Name
- ciliary microtubule associated protein 1B
- Symbol
- cimap1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to be located in cytoplasm. Predicted to be active in cytoskeleton. Is expressed in male organism; peripheral olfactory organ; and pronephros. Orthologous to several human genes including ODF3B (outer dense fiber of sperm tails 3B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 45 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63985 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa45629 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ciliary Microtubule Associated | Sperm-tail PG-rich repeat |
|---|---|---|---|
|
UniProtKB:A3KQA5
|
257 | ||
|
UniProtKB:A0A8M9PLY6
|
257 | ||
|
UniProtKB:B2GPR8
|
257 | ||
|
UniProtKB:A0A8M9P0Z2
|
158 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trim35-30-201
(1)
|
Ensembl | 1,298 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-238C7 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-1H4 | ZFIN Curated Data | |
| Encodes | EST | fj19d04 | ||
| Encodes | cDNA | MGC:63985 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191629 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195132 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195158 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_199958 (1) | 1097 nt | ||
| Genomic | GenBank:BX571879 (1) | 252198 nt | ||
| Polypeptide | UniProtKB:A0A8M9PLY6 (1) | 257 aa |
- Rayamajhi, D., Ege, M., Ukhanov, K., Ringers, C., Zhang, Y., Jung, I., D'Gama, P.P., Li, S.S., Cosacak, M.I., Kizil, C., Park, H.C., Yaksi, E., Martens, J.R., Brody, S.L., Jurisch-Yaksi, N., Roy, S. (2024) The forkhead transcription factor Foxj1 controls vertebrate olfactory cilia biogenesis and sensory neuron differentiation. PLoS Biology. 22:e3002468e3002468
- Zanardini, M., Zhang, W., Habibi, H.R. (2024) Arginine Vasotocin Directly Regulates Spermatogenesis in Adult Zebrafish (Danio rerio) Testes. International Journal of Molecular Sciences. 25(12):
- Lee, M.S., Han, H.J., Choi, T.I., Lee, K.H., Baasankhuu, A., Kim, H.T., Kim, C.H. (2023) IFT46 gene promoter-driven ciliopathy disease model in zebrafish. Frontiers in cell and developmental biology. 11:12005991200599
- Wesselman, H.M., Flores-Mireles, A.L., Bauer, A., Pei, L., Wingert, R.A. (2023) Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis. Development (Cambridge, England). 150(10):
- Wesselman, H.M., Gatz, A.E., Pfaff, M.R., Arceri, L., Wingert, R.A. (2023) Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 12(4):
- Qian, P., Kang, J., Liu, D., Xie, G. (2022) Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Frontiers in genetics. 13:851719
- Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948
- Weaver, N.E., Healy, A., Wingert, R.A. (2022) gldc Is Essential for Renal Progenitor Patterning during Kidney Development. Biomedicines. 10(12):
- Wang, Y., Ye, D., Zhang, F., Zhang, R., Zhu, J., Wang, H., He, M., Sun, Y. (2021) Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 163(2):
- Zhu, P., Qiu, Q., Harris, P.C., Xu, X., Lin, X. (2021) mtor Haploinsufficiency Ameliorates Renal Cysts and Cilia Abnormality in Adult Zebrafish tmem67 Mutants. Journal of the American Society of Nephrology : JASN. 32(4):822-836
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