Gene

fuca1.1

ID

ZDB-GENE-030131-7434

Name

alpha-L-fucosidase 1, tandem duplicate 1

Symbol

fuca1.1 Nomenclature History

Previous Names

fuca1
wu:fj17c05

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in fucosidosis. Is expressed in several structures, including EVL; epidermis; periderm; sensory system; and yolk syncytial layer. Orthologous to human FUCA1 (alpha-L-fucosidase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56379 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fuca1.1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
fucosidosis	Alliance	Fucosidosis	230000

Associated With fuca1.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018526	Glycoside hydrolase, family 29, conserved site
Domain	IPR031919	Alpha-L-fucosidase, C-terminal
Family	IPR000933	Glycoside hydrolase, family 29
Family	IPR016286	Alpha-L-fucosidase, metazoa-type
Homologous_superfamily	IPR013780	Glycosyl hydrolase, all-beta
Homologous_superfamily	IPR017853	Glycoside hydrolase superfamily