Gene

picalmb

ID
ZDB-GENE-030131-6795
Name
phosphatidylinositol binding clathrin assembly protein b
Symbol
picalmb Nomenclature History
Previous Names
  • picalm
  • picalml
  • fa01d03
  • wu:fa01d03 (1)
  • wu:fa05d03
  • wu:fb69g01
  • wu:fe17e02
  • zgc:91993
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have SNARE binding activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Predicted to be involved in clathrin-dependent endocytosis and synaptic vesicle budding from presynaptic endocytic zone membrane. Predicted to localize to clathrin-coated pit; cytoplasmic vesicle; and extrinsic component of presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human PICALM (phosphatidylinositol binding clathrin assembly protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With picalmb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid, somatic 601626
Associated With picalmb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011417 AP180 N-terminal homology (ANTH) domain
Domain IPR013809 ENTH domain
Family IPR045192 Clathrin coat assembly protein AP180-like
Homologous_superfamily IPR008942 ENTH/VHS
Homologous_superfamily IPR014712 ANTH domain superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA picalmb-203 (1) Ensembl 1,634 nt
mRNA picalmb-205 (1) Ensembl 4,903 nt
mRNA picalmb-206 (1) Ensembl 5,105 nt
ncRNA picalmb-002 (1) Ensembl 627 nt
ncRNA picalmb-003 (1) Ensembl 537 nt
ncRNA picalmb-004 (1) Ensembl 161 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations