Gene
grik1a
- ID
- ZDB-GENE-030131-6502
- Name
- glutamate receptor, ionotropic, kainate 1a
- Symbol
- grik1a Nomenclature History
- Previous Names
-
- grik1
- fv36b03
- wu:fv36b03
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have kainate selective glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to localize to kainate selective glutamate receptor complex; postsynaptic density membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in childhood absence epilepsy. Orthologous to human GRIK1 (glutamate ionotropic receptor kainate type subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
| Family | IPR001508 | Ionotropic glutamate receptor, metazoa |
| Family | IPR015683 | Ionotropic glutamate receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
| Protein | Length | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Ionotropic glutamate receptor, metazoa | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B391
|
902 | ||||||
|
UniProtKB:E9QGN5
|
904 | ||||||
|
UniProtKB:A0A8M3AWP9
|
914 | ||||||
|
UniProtKB:A0A8M3BCZ5
|
919 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grik1a-201
(1)
|
Ensembl | 3,874 nt | ||
| mRNA |
grik1a-202
(1)
|
Ensembl | 747 nt | ||
| mRNA |
grik1a-205
(1)
|
Ensembl | 3,192 nt | ||
| ncRNA |
grik1a-002
(1)
|
Ensembl | 600 nt | ||
| ncRNA |
grik1a-004
(1)
|
Ensembl | 756 nt | ||
| ncRNA |
grik1a-005
(1)
|
Ensembl | 752 nt |
Interactions and Pathways
No data available
Plasmids
No data available