Gene

phf21ab

ID

ZDB-GENE-030131-6456

Name

PHD finger protein 21Ab

Symbol

phf21ab Nomenclature History

Previous Names

phf21a
fj98d03
wu:fj98d03

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity. Involved in face development. Predicted to localize to histone deacetylase complex. Is expressed in head; nervous system; optic cup; otic vesicle; and pectoral fin. Orthologous to human PHF21A (PHD finger protein 21A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Kim et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phf21ab Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures	618725

Associated With phf21ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR019787	Zinc finger, PHD-finger
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	Zinc finger, FYVE/PHD-type	Zinc finger, PHD-finger	Zinc finger, PHD-type	Zinc finger, PHD-type, conserved site	Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M9PH61 InterPro	833
UniProtKB:A0A8M9PVB7 InterPro	861
UniProtKB:A0A8M9P6P2 InterPro	840
UniProtKB:A0A8M9PN21 InterPro	892
UniProtKB:A0A2R8QB31 InterPro	797
UniProtKB:A0A8M9PN25 InterPro	828
UniProtKB:A0A8M9PYT7 InterPro	781
UniProtKB:A0A8M9PYT2 InterPro	891

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	phf21ab-201 (1) Ensembl	Ensembl	3,367 nt	Select Tool
mRNA	phf21ab-202 (1) Ensembl	Ensembl	2,328 nt	Select Tool ZFIN BLAST
mRNA	phf21ab-203 (1) Ensembl	Ensembl	881 nt	Select Tool
mRNA	phf21ab-204 (1) Ensembl	Ensembl	260 nt	Select Tool
mRNA	phf21ab-205 (1) Ensembl	Ensembl	3,028 nt	Select Tool ZFIN BLAST
mRNA	phf21ab-206 (1) Ensembl	Ensembl	3,121 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations