Gene

mbd1b

ID
ZDB-GENE-030131-6318
Name
methyl-CpG binding domain protein 1b
Symbol
mbd1b Nomenclature History
Previous Names
  • mbd1
  • wu:fi45g12
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have methyl-CpG binding activity. Predicted to be involved in methylation-dependent chromatin silencing and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MBD1 (methyl-CpG binding domain protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mbd1b Human Ortholog
No data available
Associated With mbd1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001739 Methyl-CpG DNA binding
Domain IPR002857 Zinc finger, CXXC-type
Homologous_superfamily IPR016177 DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding domain superfamily Methyl-CpG DNA binding Zinc finger, CXXC-type
UniProtKB:Q7SZX5 673
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mbd1b-201 (1) Ensembl 3,579 nt
mRNA mbd1b-202 (1) Ensembl 3,702 nt
mRNA mbd1b-203 (1) Ensembl 393 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations