Gene

brf1b

ID
ZDB-GENE-030131-6248
Name
BRF1 general transcription factor IIIB subunit b
Symbol
brf1b Nomenclature History
Previous Names
  • fi40c10
  • wu:fi40c10
  • zgc:63497
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have RNA polymerase III type 3 promoter sequence-specific DNA binding activity and transcription factor binding activity. Involved in cerebellum development and thrombocyte differentiation. Predicted to localize to transcription factor TFIIIB complex. Is expressed in head. Orthologous to human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brf1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cerebellofaciodental syndrome Alliance Cerebellofaciodental syndrome 616202
Associated With brf1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011665 Brf1, TBP-binding domain
Domain IPR013137 Zinc finger, TFIIB-type
Domain IPR013150 Transcription factor TFIIB, cyclin-like domain
Domain IPR013763 Cyclin-like domain
Family IPR000812 Transcription factor TFIIB
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Brf1, TBP-binding domain Cyclin-like domain Cyclin-like superfamily Transcription factor TFIIB Transcription factor TFIIB, cyclin-like domain Zinc finger, TFIIB-type
UniProtKB:Q6P9Z3 693
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA brf1b-201 (1) Ensembl 3,011 nt
mRNA brf1b-203 (1) Ensembl 4,234 nt
ncRNA brf1b-002 (1) Ensembl 1,058 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations