Gene
gnl3
- ID
- ZDB-GENE-030131-616
- Name
- G protein nucleolar 3
- Symbol
- gnl3 Nomenclature History
- Previous Names
-
- id:ibd2914
- nstm (1)
- nucleostemin
- wu:fb38a04
- wu:fc55d07
- zgc:123093
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Involved in several processes, including exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neural retina development; and regulation of exit from mitosis. Predicted to localize to nucleolus. Is expressed in head; immature eye; midbrain; and somite. Orthologous to human GNL3 (G protein nucleolar 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR006073 | GTP binding domain |
Domain | IPR014813 | Guanine nucleotide-binding protein-like 3, N-terminal domain |
Domain | IPR030378 | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain |
Family | IPR050755 | TRAFAC YlqF/YawG GTPases, Ribosome Maturation |
Homologous_superfamily | IPR023179 | GTP-binding protein, orthogonal bundle domain superfamily |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain | GTP binding domain | GTP-binding protein, orthogonal bundle domain superfamily | Guanine nucleotide-binding protein-like 3, N-terminal domain | P-loop containing nucleoside triphosphate hydrolase | TRAFAC YlqF/YawG GTPases, Ribosome Maturation |
---|---|---|---|---|---|---|---|
UniProtKB:Q6DRP2
|
561 |
Interactions and Pathways
No data available
Plasmids
No data available