Gene

tmprss4b

ID

ZDB-GENE-030131-5862

Name

transmembrane serine protease 4b

Symbol

tmprss4b Nomenclature History

Previous Names

si:ch211-139a5.13
si:ch211-139a5.6 (1)
wu:fi21e09
wu:fk84e06

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have scavenger receptor activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Is expressed in integument and kidney. Orthologous to human TMPRSS4 (transmembrane serine protease 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ohler et al., 2011

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmprss4b Human Ortholog

No data available

Associated With tmprss4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018114	Serine proteases, trypsin family, histidine active site
Active_site	IPR033116	Serine proteases, trypsin family, serine active site
Domain	IPR001190	SRCR domain
Domain	IPR001254	Serine proteases, trypsin domain
Family	IPR001314	Peptidase S1A, chymotrypsin family
Homologous_superfamily	IPR009003	Peptidase S1, PA clan
Homologous_superfamily	IPR036055	LDL receptor-like superfamily
Homologous_superfamily	IPR036772	SRCR-like domain superfamily
Homologous_superfamily	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold
Repeat	IPR002172	Low-density lipoprotein (LDL) receptor class A repeat