Gene
gnai2b
- ID
- ZDB-GENE-030131-5861
- Name
- guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
- Symbol
- gnai2b Nomenclature History
- Previous Names
-
- gnai2
- fi21e06
- Galpha i2a (1)
- wu:fi21e06
- zgc:56690
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to localize to heterotrimeric G-protein complex. Is expressed in several structures, including barbel; lip; nervous system; neural tube; and tail bud. Orthologous to human GNAI2 (G protein subunit alpha i2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56690 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Pituitary adenoma, ACTH-secreting, somatic | |||
Ventricular tachycardia, idiopathic | 192605 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR001019 | Guanine nucleotide binding protein (G-protein), alpha subunit |
Family | IPR001408 | G-protein alpha subunit, group I |
Homologous_superfamily | IPR011025 | G protein alpha subunit, helical insertion |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | G-protein alpha subunit, group I | G protein alpha subunit, helical insertion | Guanine nucleotide binding protein (G-protein), alpha subunit | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|
UniProtKB:Q7ZWI5
|
347 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
gnai2b-201
(1)
|
Ensembl | 1,044 nt | ||
mRNA |
gnai2b-202
(1)
|
Ensembl | 2,618 nt |
Interactions and Pathways
No data available
Plasmids
No data available