Gene

wee2

ID
ZDB-GENE-030131-5682
Name
WEE2 oocyte meiosis inhibiting kinase
Symbol
wee2 Nomenclature History
Previous Names
  • im:5913035
  • si:ch211-238n5.5
  • wu:fi13b10
  • zgc:123074
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have protein tyrosine kinase activity. Predicted to be involved in mitotic cell cycle checkpoint and regulation of meiosis I. Predicted to localize to nucleus. Orthologous to human WEE2 (WEE2 oocyte meiosis inhibiting kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wee2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Oocyte/zygote/embryo maturation arrest 5 617996
Associated With wee2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR017164 Wee1-like protein kinase
Family IPR050339 Cell Cycle and Stress Response Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Cell Cycle and Stress Response Kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Wee1-like protein kinase
UniProtKB:Q1LX51 532
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA wee2-201 (1) Ensembl 1,922 nt
mRNA wee2-202 (1) Ensembl 1,913 nt
mRNA wee2-203 (1) Ensembl 2,021 nt
mRNA wee2-204 (1) Ensembl 1,876 nt
mRNA wee2-205 (1) Ensembl 164 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations