Gene
dyrk1ab
- ID
- ZDB-GENE-030131-5677
- Name
- dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
- Symbol
- dyrk1ab Nomenclature History
- Previous Names
-
- fi12h09
- wu:fi12h09
- wu:fi26g04
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in endothelial cell; heart; and nervous system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR044131 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A/1B, catalytic domain |
| Family | IPR050494 | Serine/threonine and dual-specificity kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Dual specificity tyrosine-phosphorylation-regulated kinase 1A/1B, catalytic domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine and dual-specificity kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B3P5
|
719 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dyrk1ab-201
(1)
|
Ensembl | 5,881 nt | ||
| mRNA |
dyrk1ab-202
(1)
|
Ensembl | 518 nt | ||
| mRNA |
dyrk1ab-203
(1)
|
Ensembl | 5,861 nt |
Interactions and Pathways
No data available
Plasmids