Gene
castor2
- ID
- ZDB-GENE-030131-5505
- Name
- cytosolic arginine sensor for mTORC1 subunit 2
- Symbol
- castor2 Nomenclature History
- Previous Names
-
- gats
- gatsl2
- sb:cb509
- wu:fc27d10
- wu:fd20f09
- wu:fe01c02
- zgc:55700
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to colocalize with GATOR2 complex. Is expressed in artery; blood; notochord; and yolk syncytial layer. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb509 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR027795 | CASTOR, ACT domain |
| Domain | IPR040778 | CASTOR1, N-terminal |
| Domain | IPR049479 | Cytosolic arginine sensor for mTORC1 subunit 1/2, ACT-like |
| Family | IPR026249 | CASTOR family |
| Family | IPR051719 | Cytosolic arginine sensor for mTORC1 |
| Homologous_superfamily | IPR045865 | ACT-like domain |
Domain Details Per Protein
| Protein | Length | ACT-like domain | CASTOR1, N-terminal | CASTOR, ACT domain | CASTOR family | Cytosolic arginine sensor for mTORC1 | Cytosolic arginine sensor for mTORC1 subunit 1/2, ACT-like |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVS6
|
329 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
castor2-201
(1)
|
Ensembl | 3,197 nt |
Interactions and Pathways
No data available
Plasmids
No data available