Gene
ago4
- ID
- ZDB-GENE-030131-5357
- Name
- argonaute RISC component 4
- Symbol
- ago4 Nomenclature History
- Previous Names
-
- Ago4 (1)
- eif2c4
- fd14f04
- wu:fd14f04
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have miRNA binding activity. Predicted to be involved in miRNA mediated inhibition of translation. Predicted to localize to P-body and RISC complex. Is expressed in several structures, including eye; fin; integument; pleuroperitoneal region; and somite. Orthologous to human AGO4 (argonaute RISC component 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003100 | PAZ domain |
| Domain | IPR003165 | Piwi domain |
| Domain | IPR014811 | Argonaute, linker 1 domain |
| Domain | IPR032472 | Argonaute linker 2 domain |
| Domain | IPR032473 | Protein argonaute, Mid domain |
| Domain | IPR032474 | Protein argonaute, N-terminal |
| Domain | IPR045246 | Argonaute-like, PIWI domain |
| Family | IPR028604 | Protein argonaute-4 |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR036085 | PAZ domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
| Protein | Length | Argonaute-like, PIWI domain | Argonaute, linker 1 domain | Argonaute linker 2 domain | PAZ domain | PAZ domain superfamily | Piwi domain | Protein argonaute-4 | Protein argonaute, Mid domain | Protein argonaute, N-terminal | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:K4IAH1
|
863 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available