Gene

lrwd1

ID

ZDB-GENE-030131-5335

Name

leucine-rich repeats and WD repeat domain containing 1

Symbol

lrwd1 Nomenclature History

Previous Names

si:dkey-261j4.9
wu:fb78b03
wu:ft31b04

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity; methyl-CpG binding activity; and methylated histone binding activity. Predicted to be involved in chromatin organization and establishment of protein localization to chromatin. Predicted to localize to chromosome. Is expressed in blastomere. Orthologous to human LRWD1 (leucine rich repeats and WD repeat domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu407 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrwd1 Human Ortholog

No data available

Associated With lrwd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR052489	Leucine-rich repeat and WD repeat-containing protein 1
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Leucine-rich repeat	Leucine-rich repeat and WD repeat-containing protein 1	Leucine-rich repeat domain superfamily	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:B0R160 InterPro	763
UniProtKB:A0A8M9PX45 InterPro	763
UniProtKB:A0A0R4IKV7 InterPro	768

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	lrwd1-201 (1) Ensembl	Ensembl	2,660 nt	Select Tool
mRNA	lrwd1-203 (1) Ensembl	Ensembl	2,307 nt	Select Tool ZFIN BLAST
ncRNA	lrwd1-002 (1) Ensembl	Ensembl	665 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations