Gene
nhp2
- ID
- ZDB-GENE-030131-533
- Name
- NHP2 ribonucleoprotein homolog (yeast)
- Symbol
- nhp2 Nomenclature History
- Previous Names
-
- nola2
- wu:fb36b10
- wu:fd61a03
- zgc:73227
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in nucleic acid metabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex and telomerase holoenzyme complex. Is expressed in several structures, including digestive system; immature eye; midbrain; retina; and segmental plate. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 2. Orthologous to human NHP2 (NHP2 ribonucleoprotein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73227 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive dyskeratosis congenita 2 | Alliance | Dyskeratosis congenita, autosomal recessive 2 | 613987 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | H/ACA ribonucleoprotein complex, subunit Nhp2-like | Ribosomal protein eL30-like superfamily | Ribosomal protein eL8/eL30/eS12/Gadd45 | Ribosomal protein eL8/Nhp2 family |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBV6
|
150 |
Interactions and Pathways
No data available
Plasmids
No data available