Gene
zbtb11
- ID
- ZDB-GENE-030131-5055
- Name
- zinc finger and BTB domain containing 11
- Symbol
- zbtb11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in neutrophil differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in head; intermediate cell mass of mesoderm; and nervous system. Orthologous to human ZBTB11 (zinc finger and BTB domain containing 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Keightley et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Keightley et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive intellectual developmental disorder 69 | Alliance | Intellectual developmental disorder, autosomal recessive 69 | 618383 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000210 | BTB/POZ domain |
Domain | IPR013087 | Zinc finger C2H2-type |
Domain | IPR041588 | Integrase zinc-binding domain |
Domain | IPR048060 | Zinc finger and BTB domain-containing protein 11, BTB/POZ domain |
Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
Protein | Length | BTB/POZ domain | Integrase zinc-binding domain | SKP1/BTB/POZ domain superfamily | Zinc finger and BTB domain-containing protein 11, BTB/POZ domain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
---|---|---|---|---|---|---|---|
UniProtKB:F1RAC1
|
1146 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
zbtb11-202
(1)
|
Havana | 4090 nt | |
ncRNA |
zbtb11-002
(1)
|
Havana | 1425 nt |
Interactions and Pathways
No data available
Plasmids
No data available