Gene
ash2l
- ID
- ZDB-GENE-030131-494
- Name
- ash2 like, histone lysine methyltransferase complex subunit
- Symbol
- ash2l Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to contribute to histone methyltransferase activity (H3-K4 specific). Involved in hematopoietic progenitor cell differentiation and primitive erythrocyte differentiation. Predicted to localize to Set1C/COMPASS complex. Orthologous to human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7141264 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ma et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR049455 | Set1/Ash2 histone methyltransferase complex subunit ASH2-like, PHD zinc finger |
| Domain | IPR053835 | Set1/Ash2 histone methyltransferase complex subunit ASH2-like, winged-helix |
| Family | IPR037353 | Histone methyltransferase complex subunit ASH2 |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Histone methyltransferase complex subunit ASH2 | Set1/Ash2 histone methyltransferase complex subunit ASH2-like, PHD zinc finger | Set1/Ash2 histone methyltransferase complex subunit ASH2-like, winged-helix | SPRY domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1RAW8
|
590 | |||||||
|
UniProtKB:A0A8M2B2E1
|
584 |
Interactions and Pathways
No data available
Plasmids
No data available