Gene
sh3gl1a
- ID
- ZDB-GENE-030131-4524
- Name
- SH3-domain GRB2-like 1a
- Symbol
- sh3gl1a Nomenclature History
- Previous Names
-
- eenb (1)
- wu:fd12b05
- wu:fy33c10
- zgc:56637
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia and malignant glioma. Is expressed in several structures, including EVL; digestive system; epidermis; hatching gland; and periderm. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56637 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acute myeloid leukemia | Alliance | Leukemia, acute myeloid | 601626 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR domain | Endophilin-A, SH3 domain | Endophilin/SH3RF | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZWA0
|
365 | ||||||
|
UniProtKB:Q1MT71
|
365 | ||||||
|
UniProtKB:A0A8M2BFR0
|
366 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sh3gl1a-201
(1)
|
Ensembl | 1,876 nt | ||
| mRNA |
sh3gl1a-202
(1)
|
Ensembl | 1,416 nt |
Interactions and Pathways
No data available
Plasmids
No data available