Gene

sec24c

ID

ZDB-GENE-030131-4487

Name

SEC24 homolog C, COPII coat complex component

Symbol

sec24c Nomenclature History

Previous Names

im:7145364
wu:fd10d12

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to act upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport and intracellular protein transport. Predicted to be located in cytoplasmic vesicle; cytosol; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in gut and head. Orthologous to human SEC24C (SEC24 homolog C, COPII coat complex component).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7145364 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Sarmah et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sec24c Human Ortholog

No data available

Associated With sec24c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006895	Zinc finger, Sec23/Sec24-type
Domain	IPR006896	Sec23/Sec24, trunk domain
Domain	IPR006900	Sec23/Sec24, helical domain
Domain	IPR007123	Gelsolin-like domain
Domain	IPR012990	Sec23/Sec24 beta-sandwich
Domain	IPR041742	Sec24-like, trunk domain
Family	IPR050550	SEC23/SEC24 family, SEC24 subfamily
Homologous_superfamily	IPR029006	ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily	IPR036174	Zinc finger, Sec23/Sec24-type superfamily
Homologous_superfamily	IPR036175	Sec23/Sec24 helical domain superfamily
Homologous_superfamily	IPR036180	Gelsolin-like domain superfamily
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily

Domain Details Per Protein

Protein	Length	ADF-H/Gelsolin-like domain superfamily	Gelsolin-like domain	Gelsolin-like domain superfamily	Sec23/Sec24 beta-sandwich	SEC23/SEC24 family, SEC24 subfamily	Sec23/Sec24, helical domain	Sec23/Sec24 helical domain superfamily	Sec23/Sec24, trunk domain	Sec24-like, trunk domain	von Willebrand factor A-like domain superfamily	Zinc finger, Sec23/Sec24-type	Zinc finger, Sec23/Sec24-type superfamily
UniProtKB:A0A0R4IMX2 InterPro	1248
UniProtKB:A0A8M2B375 InterPro	1277
UniProtKB:A0A8M6Z9C2 InterPro	1291
UniProtKB:A0A0R4IAZ9 InterPro	1300
UniProtKB:A0A8M2B330 InterPro	1271

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sec24c-202 (1) Ensembl	Ensembl	5,678 nt	Select Tool ZFIN BLAST
mRNA	sec24c-203 (1) Ensembl	Ensembl	4,239 nt	Select Tool ZFIN BLAST
mRNA	sec24c-204 (1) Ensembl	Ensembl	484 nt	Select Tool ZFIN BLAST
ncRNA	sec24c-004 (1) Ensembl	Ensembl	528 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations