Gene
pfas
- ID
- ZDB-GENE-030131-4420
- Name
- phosphoribosylformylglycinamidine synthase
- Symbol
- pfas Nomenclature History
- Previous Names
-
- fd05a06
- si:dkey-183n20.16
- wu:fd05a06
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have phosphoribosylformylglycinamidine synthase activity. Predicted to be involved in purine nucleobase biosynthetic process. Predicted to localize to cytoplasm. Is expressed in brain; digestive system; eye; heart; and muscle. Orthologous to human PFAS (phosphoribosylformylglycinamidine synthase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Li et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR010918 | PurM-like, C-terminal domain |
Domain | IPR040707 | Phosphoribosylformylglycinamidine synthase, N-terminal |
Domain | IPR041609 | Phosphoribosylformylglycinamidine synthase, linker domain |
Family | IPR010073 | Phosphoribosylformylglycinamidine synthase PurL |
Homologous_superfamily | IPR029062 | Class I glutamine amidotransferase-like |
Homologous_superfamily | IPR036604 | Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily |
Homologous_superfamily | IPR036676 | PurM-like, C-terminal domain superfamily |
Homologous_superfamily | IPR036921 | PurM-like, N-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | Class I glutamine amidotransferase-like | Phosphoribosylformylglycinamidine synthase, linker domain | Phosphoribosylformylglycinamidine synthase, N-terminal | Phosphoribosylformylglycinamidine synthase PurL | Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily | PurM-like, C-terminal domain | PurM-like, C-terminal domain superfamily | PurM-like, N-terminal domain superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q5TZ72
|
1314 |
Interactions and Pathways
No data available
Plasmids
No data available