Gene
pigp
- ID
- ZDB-GENE-030131-4041
- Name
- phosphatidylinositol glycan anchor biosynthesis, class P
- Symbol
- pigp Nomenclature History
- Previous Names
-
- dscr5 (1)
- wu:fc66d08
- zgc:73366
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Acts upstream of or within convergent extension involved in axis elongation; regulation of JNK cascade; and regulation of convergent extension involved in gastrulation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in blastomere; central nervous system; and somite. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 55. Orthologous to human PIGP (phosphatidylinositol glycan anchor biosynthesis class P).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73366 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Shao et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 55 | Alliance | Developmental and epileptic encephalopathy 55 | 617599 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPI Anchor Biosynthesis Protein | Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit | PIG-P |
|---|---|---|---|---|
|
UniProtKB:A0A2R8Q1D2
|
127 | |||
|
UniProtKB:A0A8M2BJV2
|
196 |
Interactions and Pathways
No data available
Plasmids
No data available