Gene
cdc42bpb
- ID
- ZDB-GENE-030131-3647
- Name
- CDC42 binding protein kinase beta (DMPK-like)
- Symbol
- cdc42bpb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actomyosin structure organization and peptidyl-threonine phosphorylation. Predicted to localize to cytoplasm and cytoskeleton. Orthologous to human CDC42BPB (CDC42 binding protein kinase beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Chilton-Okur-Chung neurodevelopmental syndrome | 619841 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR001180 | Citron homology (CNH) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR014930 | Myotonic dystrophy protein kinase, coiled coil |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Domain | IPR031597 | KELK-motif containing domain |
| Family | IPR050839 | Rho-associated Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | C1-like domain superfamily | Citron homology (CNH) domain | CRIB domain | KELK-motif containing domain | Myotonic dystrophy protein kinase, coiled coil | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Rho-associated Serine/Threonine Kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PBW0
|
1772 | |||||||||||||||
|
UniProtKB:Q5TZ42
|
1708 | |||||||||||||||
|
UniProtKB:A0A8M3AT38
|
1725 | |||||||||||||||
|
UniProtKB:A0A8M9P2Q2
|
1789 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdc42bpb-201
(1)
|
Ensembl | 6,650 nt | ||
| mRNA |
cdc42bpb-202
(1)
|
Ensembl | 5,919 nt |
Interactions and Pathways
No data available
Plasmids
No data available