Gene
las1l
- ID
- ZDB-GENE-030131-3625
- Name
- LAS1 like ribosome biogenesis factor
- Symbol
- las1l Nomenclature History
- Previous Names
-
- si:dkey-286f3.7
- wu:fc47c12
- wu:fi05c08
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to localize to preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Orthologous to human LAS1L (LAS1 like ribosome biogenesis factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Butterfield et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Wilson-Turner syndrome | Alliance | Wilson-Turner syndrome | 309585 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007174 | Las1 |
Domain Details Per Protein
| Protein | Length | Las1 |
|---|---|---|
|
UniProtKB:A0A8M9Q8R6
|
519 | |
|
UniProtKB:A2CF03
|
580 |
Interactions and Pathways
No data available
Plasmids
No data available