Gene
nt5c2a
- ID
- ZDB-GENE-030131-3566
- Name
- 5'-nucleotidase, cytosolic IIa
- Symbol
- nt5c2a Nomenclature History
- Previous Names
-
- nt5c2
- fc36f11
- sb:eu835
- wu:fc36f11
- wu:fc45b10
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have 5'-nucleotidase activity. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu835 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Vishnolia et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 45 | Alliance | Spastic paraplegia 45, autosomal recessive | 613162 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | HAD-like superfamily | HAD superfamily | HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase | Purine 5'-nucleotidase |
|---|---|---|---|---|---|
|
UniProtKB:E7FC21
|
561 | ||||
|
UniProtKB:A0A8M9QJJ3
|
530 | ||||
|
UniProtKB:A0A8M2B3I7
|
574 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nt5c2a-201
(1)
|
Ensembl | 3,217 nt | ||
| mRNA |
nt5c2a-202
(1)
|
Ensembl | 3,187 nt | ||
| mRNA |
nt5c2a-203
(1)
|
Ensembl | 3,102 nt |
Interactions and Pathways
No data available
Plasmids
No data available