Gene

taf2

ID

ZDB-GENE-030131-3207

Name

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Symbol

taf2 Nomenclature History

Previous Names

fc30f02
fc56a05
wu:fc30f02
wu:fc56a05

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity and transcription regulatory region DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and transcription initiation from RNA polymerase II promoter. Predicted to localize to transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TAF2 (TATA-box binding protein associated factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With taf2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 40	Alliance	Intellectual developmental disorder, autosomal recessive 40	615599

Associated With taf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR037813	Transcription initiation factor TFIID subunit 2
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR027268	Peptidase M4/M1, CTD superfamily
Homologous_superfamily	IPR042097	Aminopeptidase N-like , N-terminal domain superfamliy