Gene
psmc6
- ID
- ZDB-GENE-030131-304
- Name
- proteasome 26S subunit, ATPase 6
- Symbol
- psmc6 Nomenclature History
- Previous Names
-
- fb20g04
- wu:fb20g04
- wu:fc85c10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; ATPase activity; and peptidase activity. Predicted to be involved in positive regulation of RNA polymerase II transcriptional preinitiation complex assembly and ubiquitin-dependent ERAD pathway. Predicted to localize to cytosolic proteasome complex and proteasome regulatory particle, base subcomplex. Orthologous to human PSMC6 (proteasome 26S subunit, ATPase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101799 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003960 | ATPase, AAA-type, conserved site |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR032501 | Proteasomal ATPase, second OB domain |
| Domain | IPR041569 | AAA ATPase, AAA+ lid domain |
| Family | IPR050221 | 26S Proteasome Regulatory ATPase |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | 26S Proteasome Regulatory ATPase | AAA ATPase, AAA+ lid domain | AAA+ ATPase domain | ATPase, AAA-type, conserved site | ATPase, AAA-type, core | Nucleic acid-binding, OB-fold | P-loop containing nucleoside triphosphate hydrolase | Proteasomal ATPase, second OB domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DRD2
|
389 |
Interactions and Pathways
No data available
Plasmids
No data available