Gene
orc6
- ID
- ZDB-GENE-030131-2976
- Name
- origin recognition complex, subunit 6
- Symbol
- orc6 Nomenclature History
- Previous Names
-
- orc6l
- wu:fa94a09
- wu:fc22h10
- zgc:65798
- zgc:77185
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to localize to nuclear origin of replication recognition complex. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Is expressed in central nervous system; eye; intermediate cell mass of mesoderm; and pharyngeal arch. Orthologous to human ORC6 (origin recognition complex subunit 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65798 (1 image)
- IMAGE:6907825 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Maerz et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Meier-Gorlin syndrome 3 | Alliance | Meier-Gorlin syndrome 3 | 613803 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ORC6, first cyclin-like domain | ORC6, second cyclin-like domain | Origin recognition complex, subunit 6, metazoa/plant |
|---|---|---|---|---|
|
UniProtKB:Q6ZM36
|
256 |
Interactions and Pathways
No data available
Plasmids
No data available