Gene
supv3l1
- ID
- ZDB-GENE-030131-2838
- Name
- SUV3-like helicase
- Symbol
- supv3l1 Nomenclature History
- Previous Names
-
- wu:fc19b02
- wu:fe37e06
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable helicase activity and nucleic acid binding activity. Acts upstream of or within liver development. Predicted to be located in mitochondrial matrix and nucleus. Predicted to be part of mitochondrial degradosome. Orthologous to human SUPV3L1 (Suv3 like RNA helicase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ni et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Ni et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la010264Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| vu497Gt | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helicase, C-terminal domain-like | Mitochondrial degradasome RNA helicase subunit, C-terminal domain | P-loop containing nucleoside triphosphate hydrolase | RNA/DNA Helicase | Suv3, C-terminal domain 1 | Suv3, DEXQ-box helicase domain | Suv3, N-terminal |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A4IG62
|
763 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
supv3l1-201
(1)
|
Ensembl | 2,699 nt | ||
| ncRNA |
supv3l1-002
(1)
|
Ensembl | 575 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-226B20 | ZFIN Curated Data | |
| Encodes | EST | fc19b02 | ||
| Encodes | EST | fe37e06 | ||
| Encodes | cDNA | MGC:162283 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001083564 (1) | 2703 nt | ||
| Genomic | GenBank:BX546482 (1) | 206949 nt | ||
| Polypeptide | UniProtKB:A4IG62 (1) | 763 aa |
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Ni, T.T., Lu, J., Zhu, M., Maddison, L.A., Boyd, K.L., Huskey, L., Ju, B., Hesselson, D., Zhong, T.P., Page-McCaw, P.S., Stainier, D.Y., and Chen, W. (2012) Conditional control of gene function by an invertible gene trap in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 109(38):15389-15394
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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