Gene
nradd
- ID
- ZDB-GENE-030131-2537
- Name
- neurotrophin receptor associated death domain
- Symbol
- nradd Nomenclature History
- Previous Names
-
- ngfr
- NGFRb (1)
- wu:fb38c02
- wu:fc10h01
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable coreceptor activity; death receptor activity; and nerve growth factor binding activity. Predicted to be involved in Rho protein signal transduction. Predicted to act upstream of or within apoptotic process and signal transduction. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ozalp et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000488 | Death domain |
| Domain | IPR001368 | TNFR/NGFR cysteine-rich region |
| Domain | IPR034046 | Tumor necrosis factor receptor 16, N-terminal |
| Domain | IPR041448 | Tumor necrosis factor receptor member 16, transmembrane domain |
| Family | IPR052302 | Neurotrophin receptor-related death domain-containing protein |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Death domain | Death-like domain superfamily | Neurotrophin receptor-related death domain-containing protein | TNFR/NGFR cysteine-rich region | Tumor necrosis factor receptor 16, N-terminal | Tumor necrosis factor receptor member 16, transmembrane domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F8D4
|
413 |
Interactions and Pathways
No data available
Plasmids
No data available