Gene
srsf2b
- ID
- ZDB-GENE-030131-2420
- Name
- serine and arginine rich splicing factor 2b
- Symbol
- srsf2b Nomenclature History
- Previous Names
-
- wu:fc07d01
- zgc:55876
- zgc:77420
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human SRSF2 (serine and arginine rich splicing factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77420 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR003954 | RNA recognition motif domain, eukaryote |
| Family | IPR051106 | RNA-binding and splicing regulatory protein |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding and splicing regulatory protein | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NZT9
|
220 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
srsf2b-201
(1)
|
Ensembl | 3,553 nt |
Interactions and Pathways
No data available
Plasmids
No data available